Leprosy is a chronic infection with diverse clinical manifestations and longstanding social implications. This handbook provides a clear clinical framework for diagnosis, classification (paucibacillary vs multibacillary), and WHO-recommended multidrug therapy, alongside guidance for managing reactions and nerve damage. Rehabilitation, disability prevention, and surgical/rehabilitative options are covered to reduce long-term impairment. Chapters also examine surveillance, contact management, stigma reduction, and community reintegration strategies that are essential to control programs. Practical algorithms, pictorial diagnostic aids, and programmatic monitoring tools make this a hands-on resource for clinicians, field workers, and public-health teams.