Translating imaging technology into clinical decisions requires modality-specific interpretation and an understanding of disease-pattern recognition. Volume 2 presents clinical applications across body systems, with focused imaging protocols for trauma, oncology, vascular disease and musculoskeletal conditions. It introduces advanced modalities—MR angiography, PET/CT, elastography—and explains their indications, strengths and limitations. Case-based imaging examples and reporting templates support accurate, actionable radiology communication. Guidance on interventional imaging procedures and image-guided biopsies links diagnostics to therapeutic avenues. The volume targets radiology trainees, referring clinicians and multidisciplinary teams using imaging to guide patient care.